Leucine and ACE inhibitors as therapies for sarcopenia: a two by two factorial randomised placebo controlled trial


LACE Trial

Can Leucine and ACE inhibitors act as a therapy for sarcopenia? This is a medical research study for people aged 70 years old and over who have muscle weakness.

Sarcopenia is the loss of muscle size and strength that happens as we age. For some of us, this starts to cause problems, such as falling, or finding it more difficult to get around and do things in our daily lives. This clinical trial will investigate whether a medicine used for the heart (perindopril) and a food supplement (leucine) can help your muscles become stronger, and so improve what you are able to do.

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